Alcohol withdrawal syndrome in admitted trauma patients

Am J Surg. 2014 Nov;208(5):781-787. doi: 10.1016/j.amjsurg.2014.04.007. Epub 2014 Jun 20.

Abstract

Background: As alcohol use is highly prevalent in trauma patients, we hypothesized that a significant proportion of hospitalized trauma patients would demonstrate alcohol withdrawal (AW).

Methods: The trauma registries at a joint trauma center system from 1999 to 2008 were evaluated for patients aged at least 16 years.

Results: Of 19,369 trauma admissions, 159 patients had AW. Blood alcohol concentration (BAC) testing was performed in 31.5% of the patients. BAC was significantly higher in AW patients versus other traumas (205.7 ± 130.1 vs 102.9 ± 121.7 mg/dL). BAC was 0 in 14.4% of AW patients. As compared with other trauma patients, patients with AW had a significantly greater age (50.2 vs 42.1 years), hospital length of stay (10 vs 3 days), intensive care unit length of stay (2 vs 0 days), need for mechanical ventilation (34% vs 12.7%), and pneumonia (12% vs 2.3%). AW patients were less frequently discharged to home (59.8% vs 69.9%). Mortality was not different.

Conclusions: AW was diagnosed in few patients. Of note, it occurred in patients with an initial BAC of 0. AW is associated with adverse outcomes.

Keywords: Alcohol; Alcohol withdrawal; Trauma.

Publication types

  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Alcoholism / blood
  • Alcoholism / complications
  • Alcoholism / diagnosis
  • Biomarkers / blood
  • Ethanol / adverse effects*
  • Ethanol / blood
  • Female
  • Hospitalization
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Registries
  • Retrospective Studies
  • Substance Withdrawal Syndrome / blood
  • Substance Withdrawal Syndrome / diagnosis
  • Substance Withdrawal Syndrome / epidemiology
  • Substance Withdrawal Syndrome / etiology*
  • Wounds and Injuries / complications*
  • Young Adult

Substances

  • Biomarkers
  • Ethanol