Predictors of low milk volume among mothers who delivered preterm

J Hum Lact. 2014 Nov;30(4):425-35. doi: 10.1177/0890334414543951. Epub 2014 Jul 25.

Abstract

Background: Factors associated with successful provision of mother's own milk (MOM) for premature infants in a Japanese neonatal intensive care unit (NICU) context are not well known.

Objective: We determined the independent risk factors for low milk volume at day 4 postpartum and formula feeding at the time of NICU discharge.

Methods: We reviewed the medical records of mothers who delivered at < 32 weeks' gestation. We determined maternal, premature infant, and milk expression variables predictive of (1) day 4 postpartum milk volume being less than the cohort median and (2) formula feeding at the time of NICU discharge, reported as adjusted odds ratios (95% confidence interval).

Results: Among 85 dyads, median (quartile range) milk volume on day 4 postpartum was 153 (34-255) mL. The rate of formula feeding at discharge was 42%. Mothers delivering by cesarean (vs vaginal) delivery had 4.3-fold (1.5-12.4) greater odds of day 4 milk volume < median (P < .01). Pregnancy-induced hypertension, delayed milk expression initiation, and low pumping frequency were strongly associated with cesarean delivery. Subsequently, mothers with day 4 milk volume < median (vs ≥ median) had 7.1-fold (2.6-19.5) greater odds of formula feeding at discharge (P < .01).

Conclusion: Cesarean delivery is associated with lower milk volume on day 4 but may represent a composite of underlying risk factors for low milk volume in the early postpartum period. Further, low milk volume on day 4 is a strong correlate of lack of exclusive breast milk feeding at NICU discharge.

Keywords: breast milk; breastfeeding; cesarean delivery; lactation; preterm delivery.

MeSH terms

  • Adult
  • Breast Feeding / statistics & numerical data*
  • Female
  • Humans
  • Infant, Newborn
  • Infant, Very Low Birth Weight*
  • Intensive Care Units, Neonatal
  • Japan
  • Lactation
  • Male
  • Maternal Behavior*
  • Milk, Human / metabolism*
  • Mother-Child Relations
  • Obstetric Labor, Premature*
  • Pregnancy
  • Retrospective Studies