Postoperative instillation of mitomycin C in the treatment of recurrent pterygium

Ophthalmic Surg. 1989 Aug;20(8):580-3.


We examined retrospectively 61 eyes of 61 patients with recurrent pterygia who had been treated with excision, with or without 0.02% mitomycin C instillation, 3 to 7 years after treatment. The rates of recurrence (5% to 9%) and complications in eyes that had undergone excision and mitomycin C instillation were less than those in eyes that had had excision only. These data suggest that the postoperative instillation of 0.02% mitomycin C, twice a day for five days, may be effective and safe in the treatment of recurrent pterygium.

MeSH terms

  • Conjunctival Diseases
  • Evaluation Studies as Topic
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mitomycin
  • Mitomycins / administration & dosage
  • Mitomycins / therapeutic use*
  • Postoperative Complications
  • Pterygium / drug therapy*
  • Pterygium / surgery
  • Recurrence
  • Retrospective Studies
  • Tissue Adhesions


  • Mitomycins
  • Mitomycin