[Developing a tailored intervention: implementing recommendations for polypharmacy in multimorbid patients (PomP)]

Z Evid Fortbild Qual Gesundhwes. 2014;108(5-6):270-7. doi: 10.1016/j.zefq.2013.08.014. Epub 2013 Oct 4.
[Article in German]


Introduction: Implementation research deals with the question of how to ensure that evidence-based knowledge is put into practice. One approach is the development of "tailored interventions (TI)". These are designed to address previously identified barriers and enablers. A common definition or methodological concept for TI has not yet been established. In this paper, a concept for TI is introduced. We describe the stepwise development of an implementation intervention for GP settings where recommendations based on current evidence are provided for the treatment of multimorbid patients receiving polypharmacy. Each step will be explained and illustrated by original data.

Methods/results: A stepwise approach was used to develop a TI: problem analysis, identification and prioritisation of determinants, identification and prioritisation of strategies and the design of a complex intervention and its underlying logic model.

Discussion: The stepwise exemplary description of this tailoring strategy may support other researchers in this field when designing a TI.

Keywords: Implementation; Implementierung; Leitlinien; Polypharmakotherapie; Tailoring; guideline; knowledge translation; polypharmacy; tailoring.

MeSH terms

  • Adult
  • Chronic Disease / drug therapy*
  • Comorbidity
  • Drug Therapy, Combination / standards*
  • Evidence-Based Medicine / organization & administration
  • Female
  • General Practice / organization & administration
  • Germany
  • Health Plan Implementation / organization & administration*
  • Humans
  • Male
  • Medication Therapy Management / organization & administration*
  • Middle Aged
  • National Health Programs / organization & administration
  • Quality Assurance, Health Care / organization & administration
  • Translational Research, Biomedical / organization & administration