The Liverpool chimaera

Vox Sang. 1989;57(2):147-9. doi: 10.1111/j.1423-0410.1989.tb01153.x.


A dispermic human chimaera is described who is a fertile female XX/XY chimaera. The chimaera was discovered due to anomalies found during routine antenatal testing. The patient had two red cell populations differing in three blood group systems; ABO, Rh and MN. Analysis of cultured lymphocytes showed 70% of cells to have the 46, XY male karyotype and analysis of cultured skin cells showed 30% of cells to have the 46, XY karyotype.

Publication types

  • Case Reports

MeSH terms

  • ABO Blood-Group System / genetics
  • Adult
  • Chimera*
  • England
  • Female
  • HLA Antigens / genetics
  • Humans
  • Immunoglobulin Isotypes / genetics
  • Karyotyping
  • MNSs Blood-Group System / genetics
  • Pedigree
  • Phenotype
  • Pregnancy
  • Rh-Hr Blood-Group System / genetics


  • ABO Blood-Group System
  • HLA Antigens
  • Immunoglobulin Isotypes
  • MNSs Blood-Group System
  • Rh-Hr Blood-Group System