Coexistence of granular cell tumor and invasive ductal breast cancer in contralateral breasts: a case report

Int J Mol Sci. 2014 Jul 25;15(8):13166-71. doi: 10.3390/ijms150813166.

Abstract

Granular cell tumor (GCT) is a benign tumor of the breast that can mimic, on breast imaging, invasive carcinomas. Biological evolution of mammary GCT is unknown, especially if it is associated with an invasive carcinoma in the same or contralateral breast. This report details the morphological features of these synchronous lesions highlighting their biological characteristics and suggesting an appropriate follow up.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Breast Neoplasms / complications*
  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / pathology
  • Carcinoma, Ductal / complications*
  • Carcinoma, Ductal / diagnosis*
  • Carcinoma, Ductal / diagnostic imaging
  • Carcinoma, Ductal / pathology
  • Erb-b2 Receptor Tyrosine Kinases / metabolism
  • Female
  • Granular Cell Tumor / complications*
  • Granular Cell Tumor / diagnosis*
  • Granular Cell Tumor / diagnostic imaging
  • Granular Cell Tumor / pathology
  • Humans
  • Immunophenotyping
  • Ki-67 Antigen / metabolism
  • Ultrasonography

Substances

  • Ki-67 Antigen
  • Erb-b2 Receptor Tyrosine Kinases
  • ERBB2 protein, human