Study covered 20 females with chronic intoxication with organic solvents, who worked long as painters on industrial enterprise. To reveal clinically significant cognitive disorders, Mini-Cog scale was applied. Drawing test helped to reveal visual and spatial disorders, restults were expressed in scores. Memory was evaluated through methods "operative memory", "short-term memory", "memory for figures", "memory for images", "hearing memory"--that proved lower results in the main group of examinees. In 75% of patients with occupational diseases caused by organic solvents, moderate cognitive disorders of amnestic multifunctional type were seen. 100% of individuals having chronic intoxication with organic solvents demonstrated encephalopathy. In comparison with reference group, the main group members had more frequent 1 and 2 degrees encephalopahy.