Management of prostate cancer in older patients: updated recommendations of a working group of the International Society of Geriatric Oncology

Lancet Oncol. 2014 Aug;15(9):e404-14. doi: 10.1016/S1470-2045(14)70018-X.


In 2010, the International Society of Geriatric Oncology (SIOG) developed treatment guidelines for men with prostate cancer who are older than 70 years old. In 2013, a new multidisciplinary SIOG working group was formed to update these recommendations. The consensus of the task force is that older men with prostate cancer should be managed according to their individual health status, not according to age. On the basis of a validated rapid health status screening instrument and simple assessment, the task force recommends that patients are classed into three groups for treatment: healthy or fit patients who should have the same treatment options as younger patients; vulnerable patients with reversible impairment who should receive standard treatment after medical intervention; and frail patients with non-reversible impairment who should receive adapted treatment.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Age Factors
  • Aged
  • Aged, 80 and over
  • Androgen Antagonists / therapeutic use
  • Antineoplastic Agents, Hormonal / therapeutic use
  • Disease-Free Survival
  • Geriatric Assessment
  • Health Services for the Aged / standards
  • Humans
  • International Cooperation
  • Male
  • Practice Guidelines as Topic*
  • Prognosis
  • Prostatectomy / methods
  • Prostatectomy / mortality
  • Prostatic Neoplasms / mortality*
  • Prostatic Neoplasms / pathology
  • Prostatic Neoplasms / therapy*
  • Radiotherapy, Conformal / methods
  • Radiotherapy, Conformal / mortality
  • Risk Assessment
  • Societies, Medical
  • Survival Analysis
  • Treatment Outcome
  • Watchful Waiting


  • Androgen Antagonists
  • Antineoplastic Agents, Hormonal