Human dominant disease genes are enriched in paralogs originating from whole genome duplication

PLoS Comput Biol. 2014 Jul 31;10(7):e1003754. doi: 10.1371/journal.pcbi.1003754. eCollection 2014 Jul.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't
  • Comment

MeSH terms

  • Disease / genetics*
  • Genes, Duplicate / genetics*
  • Genome, Human / genetics*
  • Humans

Grant support

PPS acknowledges a PhD fellowship from Erasmus Mundus (Université Pierre et Marie Curie) and La Ligue Contre Le Cancer; SA and GM acknowledge a PhD fellowship from Ministry of Higher Education and Research. HI acknowledges funding from Foundation Pierre-Gilles de Gennes. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.