[The value of noninvasive serological markers in hepatitis B]

Gastroenterol Hepatol. 2014 Jul;37 Suppl 2:22-5. doi: 10.1016/S0210-5705(14)70065-2.
[Article in Spanish]


Bloodless methods (serological and imaging) for evaluating hepatic fibrosis constitute a good alternative to biopsies in the diagnosis and monitoring of the progression of chronic hepatitis C infection, but the available information for hepatitis B is scarcer. A recent literature review, however, allows us to conclude that noninvasive serological methods constitute a useful tool for the diagnosis and monitoring of the progression of fibrosis in patients with hepatitis B infection, as occurs in the case of hepatitis C. The combination of any of these methods (particularly the FibroTest) with transient elastometry increases the precision and predictive value for fibrosis in these patients.

Keywords: Fibrosis; Hepatitis B; Métodos serológicos; Serological methods.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Biomarkers / blood
  • Hepatitis B, Chronic / blood*
  • Hepatitis B, Chronic / complications
  • Humans
  • Liver Cirrhosis / blood
  • Liver Cirrhosis / etiology
  • Serologic Tests


  • Biomarkers