The utility of quantitative electroencephalography and Integrated Visual and Auditory Continuous Performance Test as auxiliary tools for the Attention Deficit Hyperactivity Disorder diagnosis

Clin Neurophysiol. 2015 Mar;126(3):532-40. doi: 10.1016/j.clinph.2014.06.034. Epub 2014 Jul 5.

Abstract

Objective: This study investigated the clinical utility of quantitative electroencephalography (QEEG) and the Integrated Visual and Auditory Continuous Performance Test (IVA+CPT) as auxiliary tools for assessing Attention Deficit Hyperactivity Disorder (ADHD).

Methods: All of 157 subjects were assessed using the Korean version of the Diagnostic Interview Schedule for Children Version IV (DISC-IV). We measured EGG absolute power in 21 channels and conducted IVA+CPT. We analyzed QEEG according to the Hz range: delta (1-4Hz), theta (4-8Hz), slow alpha (8-10Hz), fast alpha (10-13.5Hz), and beta (13.5-30Hz). To remove artifacts, independent component analysis was conducted (ICA), and the tester confirmed the results again.

Results: All of the IVA+CPT quotients showed significant differences between the ADHD and control groups. The ADHD group showed significantly increased delta and theta activity compared with the control group. The z-scores of theta were negatively correlated with the scores of IVA+CPT in ADHD combined type, and those of beta were positively correlated.

Conclusions: IVA+CPT and QEEG significantly discriminated between ADHD and control groups. The commission error of IVA+CPT showed an accuracy of 82.1%, and the omission error of IVA+CPT showed an accuracy of 78.6%.

Significance: The IVA+CPT and QEEG are expected to be valuable tools for aiding ADHD diagnosis accurately.

Keywords: Attention Deficit Hyperactivity Disorder (ADHD); Integrated Visual and Auditory Continuous Performance Test (IVA+CPT); Quantitative electroencephalography (QEEG).

Publication types

  • Evaluation Study

MeSH terms

  • Attention / physiology*
  • Attention Deficit Disorder with Hyperactivity / diagnosis*
  • Attention Deficit Disorder with Hyperactivity / physiopathology
  • Auditory Perception / physiology
  • Child
  • Electroencephalography / methods*
  • Female
  • Humans
  • Male
  • Psychiatric Status Rating Scales
  • Visual Perception / physiology