Validity and test-retest reliability of a measure of hand sensibility and manual dexterity in people with multiple sclerosis: the ReSense test

Disabil Rehabil. 2015;37(10):914-20. doi: 10.3109/09638288.2014.948128. Epub 2014 Aug 6.


Purpose: To evaluate the concurrent validity and reliability of the ReSense tool, a new clinical test aimed at determining sensory and functional deficits of the hand in people with multiple sclerosis (PwMS).

Methods: Study participants included 90 PwMS, 58 women, characterized by significant sensory symptoms in one or both hands. Thirty healthy subjects, 19 women, served as controls. The ReSense evaluation tool measures the ability to perceive and recognize texture and spatial properties of specific elements. ReSense scores were compared with the two-point discrimination (2PD), Semmes-Weinstein monofilament (SWM), Nine-Hole Peg Test (9-HPT), Box and Block Test (BBT) and the Functional dexterity (FDT) tests.

Results: The Cronbach alpha value for the ReSense test for PwMS was 0.84. The ReSense was significantly correlated with the 9-HPT; Pearson's R = -0.44 and FDT; Pearson's R = -0.35. Significant correlations were demonstrated between the ReSense score to SWM and 2PD. The strongest correlation was found with the 2PD performed on the dominant hand; Pearson's R = -0.55.

Conclusions: The ReSense is a valid tool developed for testing sensing properties of the hand in PwMS. We believe that the sensitivity and specificity values of this tool will assist the clinician to formulate decisions related to rehabilitation management of his/her patient.

Keywords: Hand; motor skills; multiple sclerosis; resense test.

Publication types

  • Validation Study

MeSH terms

  • Adult
  • Case-Control Studies
  • Female
  • Hand / physiopathology*
  • Humans
  • Male
  • Middle Aged
  • Motor Skills / physiology*
  • Multiple Sclerosis / rehabilitation*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Touch