Boron and antioxidants complex: a new concept for the treatment of kidney stones without rigorous pain

Endocr Regul. 2014 Jul;48(3):120-5. doi: 10.4149/endo_2014_03_120.


Objective: Stone disease is an increasingly common form of renal disease. Diet plays an important role in expression of the tendency to stone formation. Renal epithelial cell injury by reactive oxygen species is a pre-requisite step and the administration of natural antioxidants has been used to protect against nephrolithiasis. Considering the nutrients, boron as an ultra-trace element is revealing to enhance the antioxidant defense mechanism and along vitamin status seems to have an impact on the stone removal.

Methods: A male patient with urolithiasis received daily boron plus antioxidants supplement and asked to consume enough of the dairy serving products plus adequate liquids.

Result: Ultrasonography assessment revealed continuous stone removal or disposal without hydronephrosis with significant pain alleviation and reduction in hematuria. The lithiasic residues were collected. The 9*20 mm size of the one eliminated stone is of noteworthy.

Conclusion: Successful and comfortable kidney stone repulsion with a minor pain and bleeding indicates that this impact of boron plus antioxidants deserves further study and clarification.

Publication types

  • Case Reports

MeSH terms

  • Antioxidants / administration & dosage*
  • Boron / administration & dosage*
  • Dietary Supplements
  • Drug Therapy, Combination
  • Humans
  • Kidney Calculi / complications
  • Kidney Calculi / drug therapy*
  • Male
  • Middle Aged
  • Pain / etiology


  • Antioxidants
  • Boron