Abstract
The prevalence of the metabolic syndrome has increased in tandem with that of obesity. The metabolic syndrome is associated with structural and functional cerebral damage. A new study confirms the association between the metabolic syndrome and reduced brain volume in the absence of diabetes mellitus. Here, we highlight how vascular dysfunction potentially contributes to this brain damage.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Brain / metabolism
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Brain / pathology*
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Cerebrovascular Circulation
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Cerebrovascular Disorders / complications
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Cerebrovascular Disorders / metabolism
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Cerebrovascular Disorders / pathology*
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Humans
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Insulin Resistance*
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Metabolic Syndrome / complications
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Metabolic Syndrome / metabolism
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Metabolic Syndrome / pathology*
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Obesity / complications
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Obesity / metabolism
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Obesity / pathology*
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Organ Size