Background: The diagnostics and therapy of optic neuritis are complex and require interdisciplinary cooperation.
Aim: Compact, up-to-date recommendations for the clinician appear to be desirable.
Material and methods: A selective literature search including the authors' professional experience was carried out. An algorithm for the practical approach to optic neuritis was derived from the best available evidence.
Results: Our recommendation distinguishes between compulsory and optional investigations. Differential diagnostic cues with regard to atypical optic neuritis and other optic neuropathies are shown. Standard therapy patterns and means of escalation are suggested. Indications for referral are presented.
Conclusion: The algorithm suggested in this article provides ophthalmologists with an effective orientation aid for the complete treatment procedure of optic neuritis.