Trichofolliculoma represents abortive differentiation of pluripotent skin cells toward hair follicles. We present a case of an adult female with lobulated mass involving the tip and dorsum of the nose for the last 15 years. The systemic and radiological examinations were noncontributory. The clinical diagnosis was thought to be dermoid cyst. The fine-needle aspiration cytology of the lobulated mass was performed, and the cytology smears showed anucleate squames admixed with sebaceous cells. The possibility of a benign skin adnexal lesion was suggested. The biopsy was done, and the final diagnosis of trichofolliculoma was made. The wide local excision of the mass was performed, and no recurrence was noted during the follow-up of 1 year.
Keywords: Cytology; hair follicle; nose; sebaceous cells; skin adnexal.