Genetics of increased lifespan in Drosophila

Bioessays. 1989 Nov;11(5):132-5. doi: 10.1002/bies.950110505.


Natural selection in the laboratory has been used to produce populations of Drosophila with genetically increased lifespan. These populations have been used to determine the physiological basis of postponed ageing and its pleiotropic concomitants. It appears that many loci and a number of physiological alterations are involved in increased lifespan.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Aging / genetics*
  • Aging / physiology
  • Animals
  • Drosophila melanogaster / genetics*
  • Drosophila melanogaster / physiology
  • Genetic Linkage / genetics*
  • Genetic Linkage / physiology
  • Life Expectancy