Whole-genome mapping for high-resolution genotyping of Pseudomonas aeruginosa

S A Boers; R Burggrave; M van Westreenen; W H F Goessens; J P Hays

doi:10.1016/j.mimet.2014.07.020

Whole-genome mapping for high-resolution genotyping of Pseudomonas aeruginosa

J Microbiol Methods. 2014 Nov:106:19-22. doi: 10.1016/j.mimet.2014.07.020. Epub 2014 Aug 10.

Authors

S A Boers¹, R Burggrave², M van Westreenen¹, W H F Goessens¹, J P Hays³

Affiliations

¹ Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands.
² Piext BV., Rosmalen, The Netherlands.
³ Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Centre, Rotterdam, The Netherlands. Electronic address: j.hays@erasmusmc.nl.

PMID: 25119380
DOI: 10.1016/j.mimet.2014.07.020

Abstract

A variety of molecular typing techniques have been developed to investigate the clonal relationship among bacterial isolates, including those associated with nosocomial infections. In this study, the authors evaluated whole-genome mapping as a tool to investigate the genetic relatedness between Pseudomonas aeruginosa isolates, including metallo beta-lactamase-positive outbreak isolates.

Keywords: Molecular typing; Nosocomial infection; Pseudomonas aeruginosa; Whole-genome mapping.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cross Infection / epidemiology
Cross Infection / microbiology
Genome, Bacterial*
Genotype
Humans
Molecular Epidemiology / methods
Molecular Typing / methods*
Pseudomonas Infections / epidemiology
Pseudomonas Infections / microbiology
Pseudomonas aeruginosa / classification*
Pseudomonas aeruginosa / genetics*