De Quervain thyroiditis in the course of H1N1 influenza infection

Hippokratia. 2014 Jan;18(1):86-7.


Background/aim: Viral infections have been frequently associated with subacute (De Quervain) thyroiditis and autoimmune thyroid diseases. In the present case report we document a rare case of De Quervain thyroiditis in the course of H1N1 influenza infection.

Description of the case: A 17-year-old previously healthy female that was treated in the General Hospital of Kalamata developed an influenza-like syndrome that was accompanied by palpitations, thyroid enlargement, and increased C-reactive protein. Polymerase chain reaction assay confirmed the diagnosis of H1N1 virus infection. Serum thyroid-stimulating hormone was suppressed to zero while the levels of free thyroxine and triiodothyronine were increased. The patient was treated with non-steroidal anti-inflammatory drugs and thyroid function was gradually restored without evolving to a hypothyroid phase.

Conclusion: To our knowledge this is the second case described in the literature of De Quervain thyroiditis associated with H1N1 influenza infection.

Keywords: De Quervain thyroiditis; H1N1 virus.