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. 2014 Aug 15;9(8):e105466.
doi: 10.1371/journal.pone.0105466. eCollection 2014.

Incidence and trends of blastomycosis-associated hospitalizations in the United States

Amy E Seitz  1 , Naji Younes  2 , Claudia A Steiner  3 , D Rebecca Prevots  4
Affiliations

Incidence and trends of blastomycosis-associated hospitalizations in the United States

Amy E Seitz et al. PLoS One. .

Abstract

We used the State Inpatient Databases from the United States Agency for Healthcare Research and Quality to provide state-specific age-adjusted blastomycosis-associated hospitalization incidence throughout the entire United States. Among the 46 states studied, states within the Mississippi and Ohio River valleys had the highest age-adjusted hospitalization incidence. Specifically, Wisconsin had the highest age-adjusted hospitalization incidence (2.9 hospitalizations per 100,000 person-years). Trends were studied in the five highest hospitalization incidence states. From 2000 to 2011, blastomycosis-associated hospitalizations increased significantly in Illinois and Kentucky with an average annual increase of 4.4% and 8.4%, respectively. Trends varied significantly by state. Overall, 64% of blastomycosis-associated hospitalizations were among men and the median age at hospitalization was 53 years. This analysis provides a complete epidemiologic description of blastomycosis-associated hospitalizations throughout the endemic area in the United States.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Map of age-adjusted blastomycosis-associated hospitalization incidence in the United States.
Figure 2
Figure 2. Blastomycosis-associated hospitalization incidence and rate of blastomycosis hospitalizations per all-cause hospitalization.
Figure 3
Figure 3. Trends in blastomycosis hospitalization incidence among states with a significant annual percentage change (A) and states with no significant annual percentage change (B).
See this image and copyright information in PMC

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