Postsplenectomy sepsis

Br J Surg. 1989 Oct;76(10):1074-81. doi: 10.1002/bjs.1800761029.


This review examines the infectious consequences of elective and emergency splenectomy, highlighting the importance of infection with Streptococcus pneumoniae. The influence of splenectomy on the immune system is discussed and the efficacy of vaccines in preventing postsplenectomy sepsis is reviewed. The value of alternative methods of preventing postsplenectomy sepsis is considered.

Publication types

  • Review

MeSH terms

  • Humans
  • Infection Control
  • Infections / etiology*
  • Postoperative Complications / etiology*
  • Postoperative Complications / prevention & control
  • Splenectomy / adverse effects*
  • Vaccination