Musculoskeletal risk factors as predictors of injury in community-dwelling women

Med Sci Sports Exerc. 2014 Sep;46(9):1752-7. doi: 10.1249/MSS.0000000000000295.


Background: Participating in health-related physical activity (PA) may increase risk for musculoskeletal injury (MSI).

Purpose: This study aimed to estimate the prevalence of structural/biomechanical risk factors in community-dwelling women and associated risk for incidence of MSI in women who are physically active.

Methods: The Women's Injury study is a surveillance of PA behaviors and MSI in women age 20-83 yr. An orthopedic examination was performed before entry into the study to assess presence of structural/biomechanical risk factors. A total of 886 women completed data collection by reporting weekly PA behavior and MSI for up to 3 yr (2007-2009), with the average participant enrolled for 98 wk. To estimate MSI risk associated with each risk factor separately, time to first MSI was modeled using proportional hazard regression with time-dependent PA covariates, controlling for age, body mass index, and previous injury.

Results: Over the course of the study, 236 of the women (26.6%) reported at least one MSI that was PA related. We found a significant association between the number of high flexibility risk factors and PA-related injury at all levels of PA exposure (HR = 1.15 and confidence interval (CI) = 1.04-1.27 for moderate-to-vigorous PA; HR = 1.16 and CI = 1.05-1.28 for moderate PA; HR = 1.15 and CI = 1.04-1.27 for vigorous PA).

Conclusions: When participating at any level of PA for health benefits, women with hypermobility in multiple muscle groups or joints should be watchful for musculoskeletal symptoms and should be counseled not to ignore symptoms when they first occur.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Biomechanical Phenomena
  • Exercise*
  • Female
  • Humans
  • Incidence
  • Joint Instability / complications
  • Joint Instability / epidemiology*
  • Ligaments / physiopathology
  • Middle Aged
  • Motor Activity*
  • Muscle Strength
  • Muscle, Skeletal / physiopathology
  • Musculoskeletal System / injuries*
  • Physical Conditioning, Human / adverse effects*
  • Prevalence
  • Range of Motion, Articular*
  • Residence Characteristics
  • Risk Factors
  • Time Factors
  • Wounds and Injuries / epidemiology
  • Young Adult