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. 2014 Dec;74(6):1105-11.
doi: 10.1007/s00280-014-2559-9. Epub 2014 Aug 19.

MicroRNAs: A New Key in Lung Cancer


MicroRNAs: A New Key in Lung Cancer

Yunlong Zhang et al. Cancer Chemother Pharmacol. .


Lung cancer as a malignance has been killing numerous patients around the world annually, and small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) are the two major types, the later accounting for nearly 80 % of lung cancer. There are multiple causes for lung cancer, and more researches have been carried out to prevent, anticipate, and diagnose the cancer. MicroRNAs (miRNAs) are small non-coding RNA molecules capable of regulating expression of over 50 % of protein-coding genes. The RNA molecules are stable in tissues and blood, so it can tend to be a biomarker in anti-lung cancer. Here, this is a review on the roles of miRNAs for possible ways to prevent lung cancer in clinical trials.

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