The brassinosteroid signaling network-a paradigm of signal integration

Curr Opin Plant Biol. 2014 Oct;21:147-153. doi: 10.1016/j.pbi.2014.07.012. Epub 2014 Aug 13.

Abstract

Many hormonal and environmental signals regulate common cellular and developmental processes in plants. While the molecular pathways that transduce these signals have each been studied in detail, how these pathways are wired into regulatory networks to provide the coordinated responses has remained an outstanding question. Recent studies of the brassinosteroid signaling network have revealed extensive signal integration through direct interactions between components of different signaling pathways. In particular, a circuit of interacting transcription regulators integrates many signaling pathways to enable coordinated and coherent regulation of seedling morphogenesis by hormonal and environmental signals. The recent studies support an emerging theme that complex networks of highly integrated signaling pathways underlie the high levels of developmental plasticity and environmental adaptability of plants.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Brassinosteroids / metabolism*
  • Plant Development / physiology
  • Plant Growth Regulators / physiology*
  • Plant Physiological Phenomena
  • Receptor Cross-Talk / physiology
  • Signal Transduction / physiology*
  • Stress, Physiological / physiology

Substances

  • Brassinosteroids
  • Plant Growth Regulators