Essential oil compounds as stress reducing agents in rats

Commun Agric Appl Biol Sci. 2013;78(2):167-72.

Abstract

Essential oil compounds were studied to demonstrate their potential as stress reducing agents against rats. Rats were intraperitoneal administered with Linalool, Cineole and Thymol, respectively. Anxiety-related behaviors were determined by open field test and elevated plus maze test. Thymol reduced anxiety-related behavior of the animals. Linalool had no effect in both sexes of rats in the open field test. Thus, the results suggested that Thymol and Linalool are safe to control pets without harming non-target mammals

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acyclic Monoterpenes
  • Animals
  • Anxiety / drug therapy*
  • Anxiety / physiopathology*
  • Anxiety / psychology
  • Behavior, Animal / drug effects
  • Cyclohexanols / administration & dosage*
  • Eucalyptol
  • Female
  • Humans
  • Male
  • Monoterpenes / administration & dosage*
  • Oils, Volatile / administration & dosage*
  • Plant Oils / administration & dosage*
  • Rats
  • Stress, Physiological / drug effects
  • Thymol / administration & dosage*

Substances

  • Acyclic Monoterpenes
  • Cyclohexanols
  • Monoterpenes
  • Oils, Volatile
  • Plant Oils
  • Thymol
  • linalool
  • Eucalyptol