Diagnostic value of T2*-weighted gradient-echo MRI for segmental evaluation in cerebral venous sinus thrombosis

Clin Imaging. Jan-Feb 2015;39(1):15-9. doi: 10.1016/j.clinimag.2014.07.002. Epub 2014 Jul 12.


Objective: We evaluated the diagnostic value of gradient-echo (GRE) imaging in patients with "cerebral venous and sinus thrombosis" (CVST).

Materials and methods: In total, 130 thrombosed venous segment signal intensities in 45 patients with CVST were analyzed retrospectively using magnetic resonance imaging and magnetic resonance venography.

Results: The T2* GRE sequence had a diagnostic value for detecting acute and subacute superior sagittal sinus (SSS) thrombosis and thrombosis of the deep veins (DVs), and cortical veins (CVs; P<.05).

Conclusions: The T2* GRE sequence had a high diagnostic value for detecting both acute and subacute SSS, DV, and CV thromboses.

Keywords: Cerebral venous sinus thrombosis; Gradient-echo (GRE); Magnetic resonance imaging; Magnetic resonance venography (MRV).

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Child, Preschool
  • Cranial Sinuses / pathology*
  • Female
  • Humans
  • Infant
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Phlebography
  • Retrospective Studies
  • Sinus Thrombosis, Intracranial / pathology*
  • Young Adult