Multi-layered intra-abdominal adhesion prophylaxis following laparoscopic colorectal surgery

Surg Endosc. 2015 Jun;29(6):1400-5. doi: 10.1007/s00464-014-3813-2. Epub 2014 Aug 27.

Abstract

Background: Small bowel obstruction secondary to intra-abdominal adhesions is a frequent postoperative complication. Less invasive surgery carries a lower risk of postoperative adhesions, but adhesions may still occur after laparoscopic colorectal surgery. We present here some of our methods of adhesion prophylaxis for laparoscopic colorectal surgery.

Methods: The 167 patients who underwent laparoscopic colorectal surgery at our center from 2007 to 2012 were retrospectively reviewed. To prevent postoperative intra-abdominal adhesions, anti-adhesion barriers were placed using the half-overlap method. The rate of postoperative small bowel obstruction was compared among three groups: patients who received no adhesion prophylaxis (Group NP), patients who received single-layered adhesion prophylaxis adjacent to the incision (Group SP), and patients who received three layers of adhesion prophylaxis at different depths (Group MLP).

Results: The rate of postoperative ileus was significantly different among the three groups, at 9.7 % (6/62) in Group NP, 5.0 % (1/19) in Group SP, and 0 % (0/86) in Group MLP).

Conclusions: This retrospective analysis found that placement of multi-layered anti-adhesion barriers using the half-overlap method provided the most effective prophylaxis. Prospective clinical trials are needed to further evaluate these methods of anti-adhesion prophylaxis.

MeSH terms

  • Adult
  • Colorectal Surgery / adverse effects
  • Colorectal Surgery / methods*
  • Female
  • Humans
  • Hyaluronic Acid / therapeutic use*
  • Intestinal Obstruction / etiology
  • Intestinal Obstruction / surgery*
  • Intestine, Small / surgery
  • Laparoscopy / adverse effects*
  • Laparoscopy / methods
  • Male
  • Middle Aged
  • Postoperative Complications / prevention & control
  • Retrospective Studies
  • Tissue Adhesions / etiology
  • Tissue Adhesions / prevention & control*

Substances

  • Seprafilm
  • Hyaluronic Acid