Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Oct;18(10):451.
doi: 10.1007/s11916-014-0451-2.

Cannabinoids for Neuropathic Pain

Affiliations
Review

Cannabinoids for Neuropathic Pain

Perry G Fine et al. Curr Pain Headache Rep. .

Abstract

Treatment options for neuropathic pain have limited efficacy and use is fraught with dose-limiting adverse effects. The endocannabinoid system has been elucidated over the last several years, demonstrating a significant interface with pain homeostasis. Exogenous cannabinoids have been demonstrated to be effective in a range of experimental neuropathic pain models, and there is mounting evidence for therapeutic use in human neuropathic pain conditions. This article reviews the history, pharmacologic development, clinical trials results, and the future potential of nonsmoked, orally bioavailable, nonpsychoactive cannabinoids in the management of neuropathic pain.

Similar articles

See all similar articles

Cited by 8 articles

See all "Cited by" articles

References

    1. J Pharmacol Exp Ther. 2003 Mar;304(3):1010-5 - PubMed
    1. Curr Med Res Opin. 2007 Jan;23(1):17-24 - PubMed
    1. Mol Pharmacol. 1995 Sep;48(3):443-50 - PubMed
    1. Pain. 2008 Sep 15;138(3):667-80 - PubMed
    1. Mini Rev Med Chem. 2009 Jan;9(1):11-25 - PubMed

LinkOut - more resources

Feedback