Ureteral metastasis from prostate cancer

BMJ Case Rep. 2014 Aug 28;2014:bcr2014206736. doi: 10.1136/bcr-2014-206736.

Abstract

A 59-year-old man had an elevated prostate-specific antigen (PSA) concentration (439 ng/mL) in December 2008. We diagnosed prostatic adenocarcinoma by prostate needle biopsy. CT and MRI showed a prostatic tumour with bone and lymph node metastases. Combined androgen blockade therapy reduced the PSA level temporarily. After the PSA level gradually started to increase again and reached 27.27 ng/mL in October 2010, the patient was diagnosed with castration-resistant prostate cancer and treated with docetaxel chemotherapy. Radiological examination detected left hydronephrosis and a tumour in the left lower ureter in March 2011. Retrograde pyelography and urine cytology of class 3 from the left ureter indicated that the ureteral mass was a urothelial carcinoma. A left nephroureterectomy was performed. After the operation, the pathological examination showed a metastatic prostate carcinoma, accompanied by a decrease in the serum PSA level from 59.56 to 45.33 ng/mL.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / secondary*
  • Adenocarcinoma / surgery
  • Bone Neoplasms / secondary
  • Chemotherapy, Adjuvant
  • Diagnosis, Differential
  • Humans
  • Lymphatic Metastasis
  • Male
  • Middle Aged
  • Nephrectomy
  • Prostatic Neoplasms / pathology*
  • Ureter / surgery
  • Ureteral Neoplasms / diagnosis
  • Ureteral Neoplasms / secondary*
  • Ureteral Neoplasms / surgery