Vasopressor weaning in patients with septic shock

Crit Care Nurs Clin North Am. 2014 Sep;26(3):413-25. doi: 10.1016/j.ccell.2014.04.001. Epub 2014 May 28.

Abstract

The purpose of this article is to propose optimal weaning of vasopressors in patients with septic shock. Topics discussed include pathophysiology of sepsis and septic shock, treatment guidelines for sepsis, autoregulation of blood flow, vasopressors used in septic shock, weaning recommendations, monitor alarms in the intensive care unit, and new directions in sepsis research.

Keywords: Hypotension; Sepsis; Septic shock; Titration; Vasopressor; Wean.

Publication types

  • Review

MeSH terms

  • Dose-Response Relationship, Drug
  • Hemodynamics
  • Humans
  • Intensive Care Units
  • Norepinephrine / therapeutic use
  • Shock, Septic / drug therapy*
  • Vasoconstrictor Agents / therapeutic use*
  • Withholding Treatment

Substances

  • Vasoconstrictor Agents
  • Norepinephrine