Comparative genomic analysis at the PATRIC, a bioinformatic resource center

Methods Mol Biol. 2014;1197:287-308. doi: 10.1007/978-1-4939-1261-2_17.


The Pathosystems Resource Integration Center (PATRIC) is a genomics-centric relational database and bioinformatics resource designed to assist scientists in infectious-disease research. This method paper provides detailed instructions on using this resource to finding data specific to genomes, saving it in a personalized workspace and using a variety of interactive tools to analyze that data. While PATRIC contains many diverse tools and functionalities to explore both genome-scale and gene expression data, the main focus of this chapter is on comparative analysis of bacterial genomes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Computational Biology*
  • Databases, Genetic
  • Genomics*