Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2014 Sep 25;21(11):1349-55.
doi: 10.1016/j.phymed.2014.06.014. Epub 2014 Aug 9.

The Effects of Repeated Administration of Camphor-Crataegus Berry Extract Combination on Blood Pressure and on Attentional Performance - A Randomized, Placebo-Controlled, Double-Blind Study

Affiliations
Randomized Controlled Trial

The Effects of Repeated Administration of Camphor-Crataegus Berry Extract Combination on Blood Pressure and on Attentional Performance - A Randomized, Placebo-Controlled, Double-Blind Study

L Erfurt et al. Phytomedicine. .

Abstract

The present study investigated the effects of repeated administration of Korodin(®), a combination of camphor and crataegus berry extract, on blood pressure and attentional functioning. This study was conducted based on a randomized, placebo-controlled, double-blind design. 54 persons participated (33 female, 21 male) with a mean age of 24.3 years. Blood pressure and body mass index were in the normal range. Participants received 20 drops of either Korodin(®) or a placebo for four times with interjacent time intervals of about 10 min. Blood pressure was measured sphygmomanometrically before and after each administration. Attentional performance was quantified by using two paper-and-pencil tests, the d2 Test of Attention and Digit Symbol Test. Greater increases in blood pressure occurred after the four Korodin(®) administrations in comparison to the four placebo administrations. The performance in two parameters of d2 Test of Attention was consistently superior after the intake of Korodin(®). The excellent tolerability and safety of Korodin(®), even after a total consumption of 80 drops, was confirmed.

Keywords: Blood pressure; Camphor; Cognitive function; Complaints; Crataegus berry.

Similar articles

See all similar articles

Publication types

LinkOut - more resources

Feedback