Amanita muscaria and Amanita pantherina poisoning: two syndromes

Toxicon. 2014 Nov;90:269-72. doi: 10.1016/j.toxicon.2014.08.067. Epub 2014 Aug 27.


Amanita muscaria contains more excitatory ibotenic acid and less depressant muscimol compared to Amanita pantherina. In this study A. muscaria poisoned patients were more often confused (26/32, p = 0.01) and agitated (20/32, p = 0.03) compared to those poisoned with A. pantherina (8/17 and 5/17). Patients poisoned with A. pantherina were more commonly comatose (5/17) compared to those poisoned with A. muscaria (2/32) (p = 0.03). In conclusion, the so-called ibotenic or pantherina-muscaria syndrome might be divided into two subtypes.

Keywords: Agitation; Amanita muscaria; Amanita pantherina; Coma; Confusion; Poisoning.

MeSH terms

  • Amanita*
  • Humans
  • Mushroom Poisoning / diagnosis*
  • Mushroom Poisoning / physiopathology
  • Retrospective Studies
  • Syndrome