Marine algae-derived bioactive peptides for human nutrition and health

J Agric Food Chem. 2014 Sep 24;62(38):9211-22. doi: 10.1021/jf502420h. Epub 2014 Sep 10.


Within the parent protein molecule, most peptides are inactive, and they are released with biofunctionalities after enzymatic hydrolysis. Marine algae have high protein content, up to 47% of the dry weight, depending on the season and the species. Recently, there is an increasing interest in using marine algae protein as a source of bioactive peptides due to their health promotion and disease therapy potentials. This review presents an overview of marine algae-derived bioactive peptides and especially highlights some key issues, such as in silico proteolysis and quantitative structure-activity relationship studies, in vivo fate of bioactive peptides, and novel technologies in bioactive peptides studies and production.

Keywords: bioactivity; enzymatic hydrolysis; marine algae; novel technologies; peptides.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Chlorophyta / chemistry*
  • Humans
  • Microalgae / chemistry*
  • Nutritive Value
  • Peptides / chemistry
  • Peptides / pharmacology*
  • Phaeophyta / chemistry*


  • Peptides