The protein-sparing modified fast for obese patients with type 2 diabetes: what to expect

Cleve Clin J Med. 2014 Sep;81(9):557-65. doi: 10.3949/ccjm.81a.13128.

Abstract

The protein-sparing modified fast (PSMF) is a very-low-calorie diet containing mostly protein and little carbohydrate. This article reviews the principles of the PSMF and its potential benefits in terms of weight loss, glycemic control, insulin resistance, cardiovascular risk factors, and related complications for patients with type 2 diabetes.

Publication types

  • Review

MeSH terms

  • Blood Glucose / metabolism
  • Body Mass Index
  • Caloric Restriction*
  • Diabetes Mellitus, Type 2 / complications*
  • Dietary Carbohydrates / administration & dosage
  • Dietary Fats / administration & dosage
  • Dietary Proteins / administration & dosage*
  • Glycated Hemoglobin A / metabolism
  • Humans
  • Insulin Resistance
  • Obesity / complications
  • Obesity / diet therapy*
  • Weight Gain
  • Weight Loss

Substances

  • Blood Glucose
  • Dietary Carbohydrates
  • Dietary Fats
  • Dietary Proteins
  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human