Brown fat in humans: consensus points and experimental guidelines

Cell Metab. 2014 Sep 2;20(3):408-15. doi: 10.1016/j.cmet.2014.07.025.


As part of a current worldwide effort to understand the physiology of human BAT (hBAT) and whether its thermogenic activity can be manipulated to treat obesity, the workshop "Exploring the Roles of Brown Fat in Humans" was convened at the National Institutes of Health on February 25-26, 2014. Presentations and discussion indicated that hBAT and its physiological roles are highly complex, and research is needed to understand the health impact of hBAT beyond thermogenesis and body weight regulation, and to define its interactions with core physiological processes like glucose homeostasis, cachexia, physical activity, bone structure, sleep, and circadian rhythms.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipose Tissue, Brown / anatomy & histology*
  • Adipose Tissue, Brown / physiology*
  • Body Weight
  • Energy Metabolism
  • Fluorodeoxyglucose F18 / analysis
  • Homeostasis
  • Humans
  • Neck / anatomy & histology
  • Neck / physiology
  • Obesity / therapy
  • Positron-Emission Tomography / methods
  • Thermogenesis


  • Fluorodeoxyglucose F18