Recognizing and managing comorbidities and complications in hidradenitis suppurativa

Semin Cutan Med Surg. 2014 Jun;33(3 Suppl):S54-6. doi: 10.12788/j.sder.0093.


The list of comorbidities associated with hidradenitis suppurativa (HS) is extensive, although these diseases do not necessarily share a common causality. Among the categories of comorbidities that are observed are obesity, other skin diseases, inflammatory conditions, and genetic disorders. Complications include scarring, restricted movement resulting from scarring and fibrosis in underlying tissue, conditions associated with obstructed lymph drainage, and psychosocial issues. Adverse effects on quality of life are common and may be severe, including unemployment, deterioration of family and other social relationships, and suicidal ideation. Clinical intervention for HS must include consideration and attention to these comorbidities and complications.

Keywords: Comorbidities; dermatologic diseases; hidradenitis suppurativa; immune-mediated inflammatory diseases; obesity.

MeSH terms

  • Adult
  • Arthralgia / complications
  • Arthritis / complications
  • Cicatrix / etiology
  • Crohn Disease / complications
  • Deafness / complications
  • Down Syndrome / complications
  • Female
  • Fibrosis / etiology
  • Hidradenitis Suppurativa / complications*
  • Hidradenitis Suppurativa / pathology
  • Hidradenitis Suppurativa / psychology
  • Hidradenitis Suppurativa / therapy
  • Humans
  • Ichthyosis / complications
  • Keratitis / complications
  • Lymphedema / etiology
  • Male
  • Middle Aged
  • Obesity / complications
  • Quality of Life
  • Skin Diseases / complications
  • Young Adult

Supplementary concepts

  • Keratitis, Ichthyosis, and Deafness (KID) Syndrome