Complete genome sequence of the actinobacterium Amycolatopsis japonica MG417-CF17(T) (=DSM 44213T) producing (S,S)-N,N'-ethylenediaminedisuccinic acid

J Biotechnol. 2014 Nov 10:189:46-7. doi: 10.1016/j.jbiotec.2014.08.034. Epub 2014 Sep 3.

Abstract

We report the complete genome sequence of Amycolatopsis japonica MG417-CF17(T) (=DSM 44213(T)) which was identified as the producer of (S,S)-N,N'-ethylenediaminedisuccinic acid during a screening for phospholipase C inhibitors. The genome of A. japonica MG417-CF17(T) consists of two replicons: the chromosome (8,961,318 bp, 68.89% G+C content) and the plasmid pAmyja1 (92,539 bp, 68.23% G+C content), encoding a total of 8422 protein coding genes. Analysis of the sequence data revealed 30 clusters encoding the biosynthesis of secondary metabolites.

Keywords: Amycolatopsis; Ethylenediaminedisuccinic acid; Genome sequence; Secondary metabolites.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Actinomycetales / genetics*
  • Base Composition / genetics
  • Genome, Bacterial / genetics*
  • Molecular Sequence Data
  • Succinates / metabolism*

Substances

  • Succinates

Associated data

  • GENBANK/CP008953
  • GENBANK/CP008954