[Recurrent pregnancy losses: Etiological considerations and investigations, the point of view of the obstetrician-gynecologist]

Rev Med Interne. 2015 Mar;36(3):182-90. doi: 10.1016/j.revmed.2014.07.004. Epub 2014 Sep 5.
[Article in French]


Pregnancy loss is a general term including distinct well-defined entities: early miscarriage, late miscarriage, and stillbirth. It is important to clarify fetal loss circumstances to guide the diagnostic assessment of this issue. Etiological considerations in the presence of a fetal loss are very important to find the causes where a treatment exists and is efficient. The aim is also to explain to the couple, very affected by the event, the reason of the fetal loss and the potential risk of recurrence in a future pregnancy. In recent years, international guidelines changed and assessment of familial thrombophilia seems to be useless in this context. Feedback of the investigations will be better in a preconception consultation and multidisciplinary management of these couples is important for both therapeutic and psychological cares.

Keywords: Bilan étiologique; Early miscarriage; Etiological considerations; Fausse couche précoce; Fausse couche tardive; Fetal loss; Late miscarriage; Mort fœtale in utero; Perte fœtale; Stillbirth.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Abortion, Habitual / etiology*
  • Abortion, Habitual / therapy
  • Diagnosis, Differential
  • Female
  • Humans
  • Physicians
  • Pregnancy
  • Pregnancy Complications / therapy*
  • Risk Factors