Chronic mycobacterial meningitis due to Mycobacterium chelonae: a case report

Int J Infect Dis. 2014 Oct:27:67-9. doi: 10.1016/j.ijid.2014.04.004. Epub 2014 Sep 3.

Abstract

We report a case of chronic meningitis due to Mycobacterium chelonae. This organism is a rapidly growing Mycobacterium (RGM) and can be found worldwide in environmental sources such as soil, dust, and water. M. chelonae is an uncommon cause of meningitis; the majority of infections caused by this organism are localized cutaneous or soft tissue infections, and rarely lung infections. The organism is indistinguishable phenotypically, so we applied PCR based on the rpoB gene sequence followed by restriction fragment length polymorphism (RFLP) for molecular identification. The subsequent sequencing of RFLP products revealed 99.7% similarity with M. chelonae.

Keywords: Chronic meningitis; Mycobacterium chelonae; Rapidly growing mycobacteria.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Female
  • Humans
  • Meningitis / cerebrospinal fluid
  • Meningitis / microbiology*
  • Mycobacterium Infections, Nontuberculous / cerebrospinal fluid
  • Mycobacterium Infections, Nontuberculous / microbiology*
  • Mycobacterium chelonae / isolation & purification*
  • Young Adult