Effect of low-intensity, low-frequency ultrasound treatment on anthropometry, subcutaneous adipose tissue, and body composition of young normal weight females

J Cosmet Dermatol. 2014 Sep;13(3):202-7. doi: 10.1111/jocd.12101.


Background: Low-intensity, low-frequency ultrasound is increasingly being used for noninvasive, external body contouring as an alternative to liposuction or laser treatments.

Objectives: To evaluate the effect of chronic localized treatment with a novel ultrasound device on subcutaneous adipose tissue thickness and fat mass in young, normal weight women.

Methods: Twenty-eight females (mean age = 25.5 ± 0.66 [SE] year, mean BMI = 22.1 ± 0.37 kg/m2) underwent a 10-week bilateral treatment with the device in the gluteus-buttock-thigh area (Lipolysis program: ultrasound frequency = 150 kHz; power = 1.65 W/cm2), 48 min per session, two sessions a week. Subcutaneous adipose tissue thickness and fat mass were evaluated before and after treatment with ultrasound and dual-energy X-ray absorptiometry, respectively.

Results: Treatment was well tolerated by all participants. At the end of treatment, statistically significant reduction of subcutaneous adipose tissue thickness was found bilaterally at the gluteus and thigh site (-2.03 ÷ -2.79%). Trunk and lower limb fat mass were reduced as well (-3.48 ÷ -3.97%).

Conclusions: A 10-week, low-intensity, low-frequency localized external ultrasound treatment is effective in reducing adipose tissue in females.

Keywords: DXA; esthetic; fat; low-frequency ultrasound; low-intensity ultrasound.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Absorptiometry, Photon
  • Adult
  • Anthropometry
  • Body Composition*
  • Body Weight
  • Cosmetic Techniques*
  • Female
  • Humans
  • Subcutaneous Fat / anatomy & histology*
  • Ultrasonic Therapy / methods*