Delayed diagnosis of clear cell chondrosarcoma after total hip replacement. A case report of a rare entity encountered in common surgery

Hip Int. Jan-Feb 2015;25(1):98-100. doi: 10.5301/hipint.5000181. Epub 2014 Sep 1.


We report the case of a young female patient who received a total hip replacement due to pain in her left hip joint, misdiagnosed as degenerative arthritis. A clear cell chondrosarcoma (CCCS) in the femoral head had initially not been detected. Seven years later, a periprosthetic recurrence of CCCS close to the former femoral osteotomy occurred. Although a sample of the periprosthetic tumour had been taken for histologic analysis, the recurrence of CCCS remained misdiagnosed for almost 2 years until this rare histopathologic morphology was examined in a specialised multidisciplinary tumour centre. Finally, revision surgery with wide tumour resection margins had to be performed requiring the removal of the total hip replacement and its reconstruction using a modular megaimplant (proximal femoral replacement). Relevant facts of the CCCS as a rare entity regarding histology, treatment and differential diagnoses are discussed.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Arthroplasty, Replacement, Hip*
  • Bone Neoplasms / complications
  • Bone Neoplasms / diagnosis*
  • Chondrosarcoma / complications
  • Chondrosarcoma / diagnosis*
  • Delayed Diagnosis*
  • Diagnosis, Differential
  • Female
  • Femur Neck*
  • Humans
  • Osteoarthritis, Hip / complications
  • Osteoarthritis, Hip / surgery*
  • Postoperative Period
  • Tomography, X-Ray Computed