Post-carotid stenting reperfusion injury with blood-brain barrier disruption on gadolinium-enhanced FLAIR MRI

BMC Neurol. 2014 Sep 10;14:178. doi: 10.1186/s12883-014-0178-z.

Abstract

Background: Following carotid revascularization, an abrupt increase in cerebral blood flow may disrupt the blood-brain barrier, resulting in reperfusion injury. This damage to the blood-brain barrier may be reflected by subarachnoid enhancement on FLAIR MRI after gadolinium injection.

Case presentation: The authors present two cases of post-carotid stenting reperfusion injury that showed hyperintensity in the subarachnoid spaces on FLAIR MRI after gadolinium injection.

Conclusion: These MRI findings may represent a marker for reperfusion injury after carotid revascularization.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Blood-Brain Barrier / pathology
  • Cerebrovascular Circulation
  • Gadolinium / administration & dosage*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Reperfusion Injury / pathology*
  • Stents*

Substances

  • Gadolinium