Medication adherence and resistant hypertension

J Hum Hypertens. 2015 Apr;29(4):213-8. doi: 10.1038/jhh.2014.73. Epub 2014 Sep 11.


Non-adherence has been a major concern in the treatment of hypertension and is particularly important in understanding and intervening in patients who appear to have resistant hypertension. Relatively few studies have examined the role of non-adherence in resistant hypertension. This review will address issues related to measurement of adherence, adherence interventions and rates of non-adherence in general hypertensive populations and in patients classified as having resistant hypertension.

Publication types

  • Review

MeSH terms

  • Antihypertensive Agents / therapeutic use*
  • Blood Pressure / drug effects*
  • Drug Resistance*
  • Humans
  • Hypertension / classification
  • Hypertension / diagnosis
  • Hypertension / drug therapy*
  • Hypertension / physiopathology
  • Medication Adherence*
  • Practice Guidelines as Topic
  • Predictive Value of Tests
  • Referral and Consultation
  • Risk Factors
  • Treatment Outcome


  • Antihypertensive Agents