An update on the impact of postnatal systemic corticosteroids on mortality and cerebral palsy in preterm infants: effect modification by risk of bronchopulmonary dysplasia

J Pediatr. 2014 Dec;165(6):1258-60. doi: 10.1016/j.jpeds.2014.07.049. Epub 2014 Sep 10.


Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data from 14 randomized controlled trials. The relationship persists and is stronger in an updated analysis with data from 20 randomized controlled trials.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adrenal Cortex Hormones / adverse effects*
  • Adrenal Cortex Hormones / therapeutic use
  • Bronchopulmonary Dysplasia / mortality
  • Bronchopulmonary Dysplasia / prevention & control*
  • Cerebral Palsy / epidemiology*
  • Effect Modifier, Epidemiologic
  • Humans
  • Infant, Premature
  • Risk Assessment


  • Adrenal Cortex Hormones