The concentration of aflatoxin M1 in the mothers' milk in Khorrambid City, Fars, Iran

Adv Biomed Res. 2014 Jul 31:3:152. doi: 10.4103/2277-9175.137859. eCollection 2014.

Abstract

Introduction: Aflatoxins are secondary toxic metabolites produced by certain group of Aspergillus species in suitable conditions. These toxins are highly toxic, immunosuppressive, mutagenic, teratogenic and carcinogenic metabolites. The purpose of this study was to detection aflatoxin M1 concentration in mother's milk from rural area of Khorrambid town of Fars Province.

Materials and methods: In this study, 87 milk samples of mothers were collected by cluster sampling methods in the period between June and July 2011 and the amount of aflatoxin M1 was measured by a competitive ELISA method.

Results: From 87 mother's milk, 24 (27.6%) samples were contaminated with aflatoxin M1 with mean concentration of 0.56 ± 1.23 pg/ml (range 0.13-4.91 pg/ml).

Conclusion: The amount of aflatoxin M1 in mothers' milk was lower than 50 ng/l (Europe Union and Iranian standard). Detection of Aflatoxin M1 in mothers' milk is due to consuming contaminated food. This contamination not only threatens the health of the mothers but also has irreversible effects on the growth and health of their babies.

Keywords: Aflatoxin M1; enzyme-linked immunosorbent assay; milk; mothers; mycotoxins.