Predictive testing for Huntington disease: I. Description of a pilot project in British Columbia

Am J Med Genet. 1989 Feb;32(2):211-6. doi: 10.1002/ajmg.1320320214.

Abstract

The discovery of DNA markers linked to the gene causing Huntington disease (HD) has allowed the development of predictive testing programs for persons at-risk. A pilot program was established in British Columbia in November 1986. Ninety-five persons are currently enrolled. The major objective of this project is to introduce and evaluate a protocol for the delivery of test results to persons at-risk for HD. The criteria for entry and details of the psychosocial assessment before and after receiving a modified risk are presented. The guidelines that are developed from this project will have major applications for predictive testing programs for other late onset autosomal dominant disorders.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • British Columbia
  • DNA / genetics
  • Genetic Counseling
  • Genetic Markers
  • Humans
  • Huntington Disease / genetics*
  • Huntington Disease / psychology
  • Patient Education as Topic / methods
  • Pilot Projects
  • Risk Factors
  • Sick Role

Substances

  • Genetic Markers
  • DNA