Klippel-Trenaunay syndrome and gestational trophoblastic neoplasm

Indian Pediatr. 2014 Sep;51(9):745-6.


Background: Klippel-Trenaunay syndrome is a non-heritable venous malformation with bone and soft tissue hypertrophy and cutaneous nevi.

Case characteristics: Neonate with Klippel Trenaunay syndrome born to a mother with past history of Gestational trophoblastic neoplasm.

Observation: Antenatally, a fetal vascular malformation was identified ultrasonologically at 29 weeks gestation. Acute myeloid leukemia was diagnosed in mother at 33 weeks gestation.

Message: A rare association of Klippel Trenaunay syndrome and gestational trophoblastic neoplasm with the possible role of either hyperglycosylated Human Chorionic Gonadotropin or chemotherapy as a link is highlighted.

Publication types

  • Case Reports

MeSH terms

  • Female
  • Gestational Trophoblastic Disease*
  • Humans
  • Infant, Newborn
  • Klippel-Trenaunay-Weber Syndrome*
  • Male
  • Pregnancy
  • Vascular Malformations*