Bridging the gap between academic research and regulatory health risk assessment of Endocrine Disrupting Chemicals

Curr Opin Pharmacol. 2014 Dec:19:99-104. doi: 10.1016/j.coph.2014.08.005. Epub 2014 Sep 18.

Abstract

Regulatory risk assessment is traditionally based primarily on toxicity studies conducted according to standardized and internationally validated test guidelines. However, health risk assessment of endocrine disrupting chemicals (EDCs) is argued to rely on the efficient integration of findings from academic research. The aim of this review was to provide an overview of current developments to facilitate the use of academic research in regulatory risk assessment of chemicals and how certain aspects of study design and reporting are particularly important for the risk assessment process. By bridging the gap between academic research and regulatory health risk assessment of EDCs, scientific uncertainty in risk assessment conclusions can be reduced, allowing for better targeted policy decisions for chemical risk reduction.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Decision Making
  • Endocrine Disruptors / toxicity*
  • Government Regulation
  • Humans
  • Research Design*
  • Risk Assessment* / legislation & jurisprudence

Substances

  • Endocrine Disruptors