Functional nanomaterials can optimize the efficacy of vaccines

Small. 2014 Nov;10(22):4505-20. doi: 10.1002/smll.201401707. Epub 2014 Sep 19.

Abstract

Nanoscale materials can improve the efficacy of vaccines. Herein we review latest developments that use nanomaterials for vaccines. By highlighting the relationships between the nanoscale physicochemical characteristics and working mechanisms of nanomaterials, this paper shows the current status of the developments where researchers employ functional nanomaterials as vector and/or immunoregulators for vaccines. It also provides us some clues for improving the design and application of nanomaterials to optimize the efficacy of vaccines.

Keywords: carriers; immune responses; immunoregulators; nanomaterials; vaccines.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Humans
  • Nanostructures*
  • Vaccines* / administration & dosage

Substances

  • Vaccines